A Clinically Advanced Approach for Detecting Fetal Chromosomal Abnormalities
Chromosomal abnormalities are among the most significant contributors to fetal structural anomalies, developmental disorders, and adverse pregnancy outcomes. Conventional prenatal diagnostic technologies, primarily karyotyping and chromosomal microarray (CMA) have played central roles in clinical genetics, yet both are limited in their ability to detect the full spectrum of fetal genomic alterations. Increasing evidence from international […]
Recurrent Miscarriage Diagnosis: A Clinical Perspective and Solutions
Recurrent pregnancy loss (RPL) remains one of the most challenging conditions in reproductive medicine, affecting approximately 1–2% of couples worldwide. Among all etiologies, chromosomal abnormalities in the embryo, including aneuploidies, structural rearrangements, and pathogenic copy number variations (CNVs), constitute the largest identifiable cause, particularly during the first trimester, when over 80% of miscarriages occur. Chromosomal […]
